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1988 1
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1992 2
1997 1
2000 2
2002 1
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2006 1
2007 3
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Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer.
Douillard JY, Siena S, Cassidy J, Tabernero J, Burkes R, Barugel M, Humblet Y, Bodoky G, Cunningham D, Jassem J, Rivera F, Kocákova I, Ruff P, Błasińska-Morawiec M, Šmakal M, Canon JL, Rother M, Oliner KS, Tian Y, Xu F, Sidhu R. Douillard JY, et al. Ann Oncol. 2014 Jul;25(7):1346-1355. doi: 10.1093/annonc/mdu141. Epub 2014 Apr 8. Ann Oncol. 2014. PMID: 24718886 Free article. Clinical Trial.
BACKGROUND: The Panitumumab Randomized trial In combination with chemotherapy for Metastatic colorectal cancer to determine Efficacy (PRIME) demonstrated that panitumumab-FOLFOX4 significantly improved progression-free survival (PFS) versus FOLFOX4 as first-line treatment …
BACKGROUND: The Panitumumab Randomized trial In combination with chemotherapy for Metastatic colorectal cancer to determine Efficacy (PRI
Consumer credit, chronic disease and risk behaviours.
Dean LT, Knapp EA, Snguon S, Ransome Y, Qato DM, Visvanathan K. Dean LT, et al. J Epidemiol Community Health. 2019 Jan;73(1):73-78. doi: 10.1136/jech-2018-211160. Epub 2018 Oct 15. J Epidemiol Community Health. 2019. PMID: 30322882 Free PMC article.
BACKGROUND: Credit scores have been identified as a marker of disease burden. ...Other health behaviours were not significantly associated. Compared with high prime credit, subprime credit score was significantly associated with a 15%-70% increased ris …
BACKGROUND: Credit scores have been identified as a marker of disease burden. ...Other health behaviours were not significantly assoc …
Developing Therapy for Transthyretin Amyloidosis.
Campbell CM, Zhang K, Lenihan DJ, Witteles R. Campbell CM, et al. Am J Med. 2022 Apr;135 Suppl 1:S44-S48. doi: 10.1016/j.amjmed.2022.01.002. Epub 2022 Jan 22. Am J Med. 2022. PMID: 35077703 Review.
In addition, we discuss emerging ATTR therapies including improvements in drug delivery methods, antibodies to break down deposited amyloid fibrils, and gene editing. ATTR is a prime example of how an understanding of the pathophysiological basis of disease can lead to eff …
In addition, we discuss emerging ATTR therapies including improvements in drug delivery methods, antibodies to break down deposited amyloid …
A patent perspective on chikungunya.
Dapurkar D, Telang M. Dapurkar D, et al. Acta Trop. 2019 Nov;199:105131. doi: 10.1016/j.actatropica.2019.105131. Epub 2019 Aug 8. Acta Trop. 2019. PMID: 31401192 Review.
In the vaccines category, vaccines based on viral vectors appear to be emerging as the preferred vaccine platform with the majority of patents filed in the years 2014-2017. Corporate sector has the most patent filings to its credit, followed closely by academic institution …
In the vaccines category, vaccines based on viral vectors appear to be emerging as the preferred vaccine platform with the majority of paten …
Editorial: Generative artificial intelligence as a plagiarism problem.
Dien J. Dien J. Biol Psychol. 2023 Jul;181:108621. doi: 10.1016/j.biopsycho.2023.108621. Epub 2023 Jun 24. Biol Psychol. 2023. PMID: 37356702
This editorial addresses the potential impact of such programs on scientific publishing as it relates to the journal Biological Psychology. Using chatGPT as an example, it makes the case that a prime concern is its implications for facilitating plagiarism. It briefly outli …
This editorial addresses the potential impact of such programs on scientific publishing as it relates to the journal Biological Psychology. …
Evidence for a credit-card-swipe mechanism in the human PC floppase ABCB4.
Prescher M, Bonus M, Stindt J, Keitel-Anselmino V, Smits SHJ, Gohlke H, Schmitt L. Prescher M, et al. Structure. 2021 Oct 7;29(10):1144-1155.e5. doi: 10.1016/j.str.2021.05.013. Epub 2021 Jun 8. Structure. 2021. PMID: 34107287 Free article.
When the hydrophilic amino acids from ABCB4 are changed to the analogous but hydrophobic ones from ABCB1, the stimulation of ATPase activity by 1,2-dioleoyl-sn-glycero-3-phosphocholine, as a prime example of PC lipids, is strongly diminished, whereas the modulation capabil …
When the hydrophilic amino acids from ABCB4 are changed to the analogous but hydrophobic ones from ABCB1, the stimulation of ATPase activity …
Cover Picture and Issue Information.
[No authors listed] [No authors listed] J Evol Biol. 2021 Jun;34(6):853-855. doi: 10.1111/jeb.13468. J Evol Biol. 2021. PMID: 34145684 Free article.
Photo Credit: Pekka Tuuri. Fruciano et al. Cichlid fi sh (in the photo Amatitlania sp.) and social insects (such as Bombus balteatus) are prime examples of organisms being studied with increasingly sophisticated and powerful tools, thus informing our understanding o …
Photo Credit: Pekka Tuuri. Fruciano et al. Cichlid fi sh (in the photo Amatitlania sp.) and social insects (such as Bombus balteatus) …
Culture and Unmerited Authorship Credit: Who Wants It and Why?
Ren X, Su H, Lu K, Dong X, Ouyang Z, Talhelm T. Ren X, et al. Front Psychol. 2016 Dec 27;7:2017. doi: 10.3389/fpsyg.2016.02017. eCollection 2016. Front Psychol. 2016. PMID: 28082940 Free PMC article.
Next, we found that collectivistic scientists were more likely to add unmerited coauthors than individualistic scientists, both between cultures (Studies 2-3) and within cultures (Study 4). Finally, we found that priming people with collectivistic self-construal primes
Next, we found that collectivistic scientists were more likely to add unmerited coauthors than individualistic scientists, both between cult …
Arsenic contamination, impact and mitigation strategies in rice agro-environment: An inclusive insight.
Moulick D, Samanta S, Sarkar S, Mukherjee A, Pattnaik BK, Saha S, Awasthi JP, Bhowmick S, Ghosh D, Samal AC, Mahanta S, Mazumder MK, Choudhury S, Bramhachari K, Biswas JK, Santra SC. Moulick D, et al. Sci Total Environ. 2021 Dec 15;800:149477. doi: 10.1016/j.scitotenv.2021.149477. Epub 2021 Aug 9. Sci Total Environ. 2021. PMID: 34426348 Review.
Arsenic (As) contamination and its adverse consequences on rice agroecosystem are well known. Rice has the credit to feed more than 50% of the world population but concurrently, rice accumulates a substantial amount of As, thereby compromising food security. ...The potenti …
Arsenic (As) contamination and its adverse consequences on rice agroecosystem are well known. Rice has the credit to feed more than 5 …
End of Life Care's Ongoing Evolution.
Fink-Samnick E. Fink-Samnick E. Prof Case Manag. 2020 May/Jun;25(3):111-131. doi: 10.1097/NCM.0000000000000417. Prof Case Manag. 2020. PMID: 32235194
With end-of-life care treatment and processes continuing to receive prime industry attention, case managers must be knowledgeable of the moving parts of this arena. ...
With end-of-life care treatment and processes continuing to receive prime industry attention, case managers must be knowledgeable of …
71 results